Free shipping on your first order to the USA & Canada We ship worldwide with tracking, 3–5 business days

Ease your mind. Ease your mood.

Natural support for a calm, balanced mood.

Seven traditional botanicals and fulvic minerals, brought together for everyday mood support and emotional wellbeing.*

  • Clinically studied
  • Doctor formulated
  • Made in Canada
  • 120 vegetarian capsules per bottle
Choose your supply →

One time purchase · Free shipping on your first order to the USA & Canada

Use consistently as directed. Individual results vary.

Mood Effex mood support, 120 vegetarian capsules
Made in CanadaNatural ingredients
Health Canada RegisteredNPN 80047565 · What’s an NPN?
90-Day ReturnsNo questions asked

A thoughtful daily routine

Botanical care for everyday balance.

Supports a calm, balanced mood and everyday emotional wellbeing.* Mood Effex combines seven botanical extracts with CLE fulvic mineral extract. Explore the formula, read the label, and choose the supply that suits you.

Explore the ingredients ↓

Product documentation

Certificate of Analysis (CoA)

The laboratory report for Mood Effex lot 183411M00 (expiry December 2028), including capsule weight checks and microbiological testing.

View the Mood Effex CoA ↗

Customer stories

What Mood Effex customers say

★★★★★
“I’ve struggled with anxiety since my teens and mild depression in my 20s. Mood Effex gave me clarity and calm without making me feel numb. I finally feel like myself again.”
Jessica MAge 29, Seattle, USA
★★★★★
“I’ve tried both prescription meds and natural approaches. Mood Effex is the first that noticeably reduced my anxiety and lifted that low-grade depression I couldn’t shake.”
Daniel RAge 42, Toronto, Canada
★★★★★
“After two weeks on Mood Effex, I found myself smiling more and waking up without that heavy feeling in my chest. It’s honestly changed my life.”
Amira HAge 35, London, UK

Individual results vary and these experiences do not predict your results.

Choose your supply

Choose what works for you.

All prices are in US dollars. No subscription.

Start here

One bottle

120 capsules

$39.95

$39.95 per bottle

 

Buy one bottle

View return terms

Buy 2, Get 1 Free

Three bottles

360 capsules

$79.90

$26.63 per bottle

$119.85 if bought individually · Save $39.95

Buy three bottles

View return terms

Buy 3, Get 2 Free

Five bottles

600 capsules

$119.85

$23.97 per bottle

$199.75 if bought individually · Save $79.90

Buy five bottles

View return terms

Free shipping on your first order to the USA & Canada ($19.95 after that). We ship worldwide with tracking, 3–5 business days. Secure checkout.

Ingredients

Seven botanicals. One daily routine.

St. John’s wort, morinda, albizzia, tribulus, spikenard, dong quai and nutgrass, complemented by fulvic mineral extract.*

View the full supplement facts ↗

St. John’s wort
St. John’s wort
Morinda root
Morinda root
Albizzia flower
Albizzia flower
Tribulus
Tribulus
Spikenard root
Spikenard root
Dong quai
Dong quai
Nutgrass root
Nutgrass root
Fulvic mineral extract
Fulvic mineral extract

Know what you're choosing

Our Doctor Team: Real Expertise. Personal Care.

  • Dr. Stacey Miller, ND
    Dr. Stacey Miller, NDChief Scientific FormulatorPortland, Oregon, USA
  • Dr. Étienne Callebout, MD
    Dr. Étienne Callebout, MDMedical Advisor (in memoriam)London, UK

Supplement facts ↗

Questions? Email info@cleholistichealth.com or call Toll Free (US & Canada) 1-888-788-8098.

FAQ

A few helpful answers.

Why is natural health under pressure, and what does it mean for me?

Increasing government regulations, licensing requirements, compliance costs and financial pressures are making it increasingly difficult for independent, plant-based health companies like ours to survive. Our products already go through Certificates of Analysis (COAs), independent third-party laboratory testing, ingredient verification and purity testing, and our applicable products carry Health Canada Natural Product Numbers (NPNs). We cannot predict how future regulatory changes may affect our ability to continue offering every formulation, so if our products have made a difference in your life, we encourage you to keep your regular supply on hand. Read our founder’s full note.

What is Mood Effex?

Mood Effex is a botanical supplement with seven traditional herbs and fulvic mineral extract, designed for everyday mood support and emotional wellbeing.*

What is natural medicine, and how does naturopathy fit in?

Natural medicine is a whole way of thinking about health—one that works with your body instead of just suppressing symptoms. It draws on plant extracts, minerals, nutrition, and lifestyle to support the body’s own systems: circulation, digestion, mood, sleep, immunity. It’s the tradition behind products like Mood Effex, and it’s been used for generations.

Naturopathy is the professional form of that tradition. A licensed naturopathic doctor assesses your whole picture—diet, stress, history, labs—and builds an individualized plan using natural therapies, working alongside your family doctor when needed.

Simply put: natural medicine is the philosophy; naturopathy is the profession that practices it. A product like Mood Effex is natural medicine you can use on your own—it supports your body’s normal function, but it doesn’t replace care from a licensed practitioner or your doctor.

How do I take Mood Effex?

Adults: take 2 capsules before breakfast and 2 before dinner, or as directed by your healthcare professional. Follow the product label. See supplement facts ↗

When will I notice a difference?

Everyone is different. Use Mood Effex consistently as directed. Individual results vary.

Can Mood Effex be taken alongside prescribed medication, or by itself?

Talk to your doctor or pharmacist before use if you take any medication. Mood Effex contains St. John’s wort, which can interact with antidepressants, birth control pills, and many other medicines. Do not combine it with antidepressants unless your prescriber specifically approves. Never stop or change prescribed treatment on your own.

What does the NPN number mean?

NPN stands for Natural Product Number, an eight digit product licence number issued by Health Canada. Licensed products are assessed for safety, efficacy and quality under their recommended conditions of use. Mood Effex’s NPN is 80047565. An NPN is a Canadian licence; it does not mean approval by the US FDA.

What is the Certificate of Analysis (CoA)?

A lab report showing the product was tested for quality and purity. View the Mood Effex CoA ↗

Is this a subscription?

No. These are one time purchases.

What payment methods do you accept?

Visa, Mastercard, American Express and PayPal.

What are the shipping and return terms?

Free shipping on your first order to the USA and Canada, then $19.95 per order. We ship worldwide with tracking, 3–5 business days. 90 day returns, no questions asked; shipping is not refunded. Contact info@cleholistichealth.com for return instructions.

A note from our founder

Natural Health Is Under Pressure. Your Right to Choose Matters.

For over 17 years, CLE Holistic Health has stood for one fundamental belief: Everyone deserves the freedom to choose natural solutions for their health and well-being.

Today, that freedom faces growing challenges.

Increasing government regulations, licensing requirements, compliance costs and financial pressures are making it increasingly difficult for independent, plant-based health companies like ours to survive.

We are also deeply concerned about the influence of powerful pharmaceutical interests and the challenges smaller natural health companies face in an industry dominated by large corporations.

Read the full note

We Have Always Put Quality, Safety and Efficacy First

Our products are already subject to extensive quality assurance measures, including Certificates of Analysis (COAs), independent third-party laboratory testing, ingredient verification, purity testing and additional quality-control procedures.

Our formulations are developed with a commitment to quality, consistency and efficacy, using carefully selected botanical extracts and our proprietary Fulvic Mineral Extract.

Our applicable products carry Health Canada Natural Product Numbers (NPNs), reflecting regulatory review of their authorized uses, safety and quality.

We support responsible oversight. However, we believe additional regulatory burdens should be proportionate, evidence-based and fair to established companies already investing heavily in product quality and consumer safety.

The future of natural health products cannot be taken for granted.

While CLE Holistic Health remains committed to serving you, we cannot predict how future regulatory changes may affect our ability to continue offering every formulation.

A Personal Message to Our Loyal Customers

Since 2009, thousands of customers worldwide have trusted our Canadian-made, professional-grade botanical formulations. Many share encouraging experiences about how our products have supported their health and daily well-being.

If our products have made a difference in your life, please continue supporting us by purchasing your regular supply while your preferred formulations remain available.

Every purchase helps us maintain our rigorous quality standards, support ongoing testing and preserve access to the natural health products you trust.

We believe natural health products and conventional medicine both deserve a place in healthcare. Consumers should have the freedom to make informed choices without unnecessary barriers.

Natural health should remain a choice, not become a privilege.

To our loyal customers worldwide, thank you for your trust, your loyalty and your continued support.

Together, we can help protect the future of natural health.

Steven KaliaFounder & Managing Director
CLE Holistic Health
Canadian Made Since 2009
www.moodeffex.com

Mood Effex. Ease your mind. Ease your mood.

One clear formula. Three straightforward options.

Choose your Mood Effex supply →

CLE Holistic Health · Vancouver, BC, CanadaOrder by phone: Toll Free (US & Canada) 1-888-788-8098info@cleholistichealth.com

Questions? Ready to order? Call us. We answer right away.

Get help with our products, place an order by phone, or check on an order. Any time, 7 days a week.

US & Canada · Toll Free1-888-788-8098
Outside US & Canada1-236-801-5888
Call Now
Frequently Asked Questions

Your Questions. Our Commitment to Transparency.

We understand that choosing a natural health supplement is an important decision. You want to know who you’re buying from, what makes the products different, whether they work and whether you can trust the company behind them. Here are some honest answers to the questions we hear most often.

Still skeptical? We understand. Ask us anything before you buy.Real answers from our team, with no pressure or obligation to purchase.

Ask us a question
1.I’ve never heard of CLE Holistic Health. Why should I trust your company?

CLE Holistic Health has been developing natural health formulations since 2009.

Our focus has always been on carefully selected botanical ingredients, proprietary formulations, quality manufacturing and product consistency.

Our Canadian licensed products carry Health Canada Natural Product Numbers (NPNs), and we use independent laboratory testing as part of our quality assurance process.

We’re committed to building lasting relationships with customers, not simply making a one time sale.

2.I’ve tried natural supplements before and they didn’t work. Why would yours be different?

We understand your skepticism.

CLE Holistic Health develops proprietary formulations combining selected botanical extracts with our specialized fulvic mineral extract.

Our approach focuses on how ingredients work together within a formulation rather than relying on a single ingredient.

However, everyone’s body is different, and no supplement can guarantee the same results for every person.

3.What makes your formulations different from ordinary supplements?

Our formulations are designed around carefully selected botanical combinations and our proprietary fulvic mineral infusion approach.

We emphasize ingredient sourcing, formulation consistency, manufacturing quality and independent testing.

Our goal is to create thoughtfully formulated products rather than simply offer another generic supplement.

4.Are your products clinically tested and scientifically supported?

Our formulations include botanical ingredients that have been the subject of scientific research.

We also maintain product quality documentation, including applicable laboratory testing and Certificates of Analysis.

It’s important to distinguish research on individual ingredients from clinical trials on a finished formulation. We encourage customers to review the specific evidence available for each product.

5.How long will it take before I notice results?

Natural health products are designed for consistent daily use, and individual experiences vary depending on the product, personal health, lifestyle and consistency of use.

We recommend following the product directions for at least 60 to 90 days and reviewing your progress with your healthcare provider.

We encourage customers to maintain realistic expectations.

6.Are your supplements safe to take with my prescription medication?

Natural supplements can interact with prescription medications.

If you take medication for blood pressure, blood sugar, mood or another medical condition, speak with your healthcare professional before starting a supplement.

Never stop, reduce or change prescribed medication without medical supervision.

7.Do your products replace prescription medications?

No.

CLE Holistic Health supplements are intended to support specific aspects of health and wellness. They are not substitutes for prescribed medical treatment.

Customers should continue following their healthcare professional’s advice.

8.Why do customers continue purchasing your products?

We have historically reported a customer reorder rate exceeding 90%.

We believe repeat purchasing reflects customer interest in our formulations and the relationships we have developed over the years.

However, repeat purchasing is not clinical proof that a product will work for everyone.

9.What if I purchase a product and I’m not satisfied?

We offer 90-day returns, no questions asked. If Mood Effex is not right for you, you can return it within 90 days of the date you receive your order for a refund of the product price.

Shipping costs are not refunded, and return shipping is paid by the customer.

Please review our full return policy before ordering for the applicable conditions and instructions.

10.Can I speak with someone before placing an order?

Absolutely.

We understand that customers may have questions about ingredients, product selection, quality or ordering.

Our team is available to provide product information and help you make an informed purchasing decision.

There is no pressure or obligation to purchase.

Email: info@cleholistichealth.com
Website: www.moodeffex.com

11.Why should I choose CLE Holistic Health over a less expensive supplement?

Price is important, but so are formulation quality, ingredient sourcing, testing and manufacturing standards.

Our focus is on proprietary botanical combinations, specialized mineral infusion and consistent quality.

We encourage customers to compare ingredient labels, dosages, testing standards and available evidence before making a decision.

12.Is CLE Holistic Health too good to be true?

We understand why customers ask.

The supplement industry is full of exaggerated promises, and we believe consumers deserve clear information.

We do not believe in promising overnight miracles or guaranteed outcomes.

Our commitment is to provide thoughtfully developed formulations, transparent product information and responsive customer support.

Have another question? Contact our team at info@cleholistichealth.com. We’re happy to help you make an informed decision.

Questions? Ready to order? Call us. We answer right away.

Get help with our products, place an order by phone, or check on an order. Any time, 7 days a week.

US & Canada · Toll Free1-888-788-8098
Outside US & Canada1-236-801-5888
Call Now